scd1 inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T71175	SCD1 Inhibitor
	SCD1 Inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.
T38683	SCD1 inhibitor-3	SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a	Dehydrogenase
	SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesit...		Dehydrogenase
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T12863	SCD1 inhibitor-1		Others
	SCD1 inhibitor-1 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase-1 (SCD1).		Others
T2650	MK-8245		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T4515	A939572		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T16068	MF-438		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T1869	PluriSIn 1	NSC 14613,PluriSIn #1,PluriSln 1	Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.		Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T13356	XEN723		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T9722	YTX-465		Stearoyl-CoA Desaturase (SCD)
	YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM).		Stearoyl-CoA Desaturase (SCD)
T14878	CAY10566		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally ...		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T61841	SCD1-IN-1
	SCD1-IN-1, a potent inhibitor of SCD1 (IC50: 5.8 nM), is valuable in dermatologic research [1].
T79262	SSI-4		Stearoyl-CoA Desaturase (SCD)
	SSI-4 is a Stearoyl CoA desaturase 1 (SCD1) inhibitor that can be labeled with carbon-11 (11C) for use as a ligand in small animal in vivo PET/CT imaging studies of SCD1 [1].		Stearoyl-CoA Desaturase (SCD)
T41253	Sterculic acid
	Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
T38844	MK-8245 Trifluoroacetate
	MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect...